Mechanisms of action of trypsin and chymotrypsin

The action of tyrosinase on chymotrypsin, trypsin, and pepsin.

The action of the enzyme tyrosinase on proteins has recently been made the subject of a study by Sizer (1). He has claimed that among a variety of proteins tested those which contained tyrosine could be oxidized by tyrosinase either directly or after pretreatment with trypsin. The proteins most susceptible to the action of tyrosinase were said to be the proteolytic enzymes chymotrypsin, trypsin...

extraction and acetylation of purified trypsin from bovin pancreas and study of some its physico-chemical properties

آنزیم تریپسین در شرایط قلیایی ناپایدار می باشد .و فعالیت پروتئولیتیکی تریپسین منجربه خود هضمی آن در جایگاههای خاصی می گردد. بنابر این آنزیمی با ناپایداری بالا محسوب میگردد. در سالهای اخیر موفق شدند که با ایجاد تغیرات شیمیایی با اضافه کردن فلزات خاص ، کلسیم و یا عمل استیلاسیون منجر به افزایش پایداری آنزیم تریپسین گردند. مطالعات در حال حاضر نشان می دهد که تریپسین استیله شده فعالیت آنزیمی خود را ...

The plasmin inhibitor of human plasma. IV. Its action on plasmin, trypsin, chymotrypsin, and thrombin.

Purified al-proteolytic inhibitor from human plasma was shown to inhibit trypsin, chymotrypsin, plasmin, and thrombin. This inhibitor is probably identical with the inhibitor previously known as serum trypsin inhibitor, al-antitrypsin, or antiplasmin. The enzymes were affected by the inhibitor via two different mechanisms. Trypsin and chymotrypsin reacted instantaneously in stoichiometric manne...

Fate of trypsin and chymotrypsin in the human small intestine.

Interaction of cY,-Macroglobulin with Trypsin, Chymotrypsin, Plasmin, and Papain’

The interaction ae-macroglobulin with four proteinases has been investigated by binding assays and by gel electrophoresis. At pH 7.65 the binding ratios of the proteinase-cwa-macroglobulin complexes were found to be 2:l (trypsin and papain), 1.4:1 (chymotrypsin), and 1:l (plasmin). The progressive decrease in the stoichiometry of the three seryl proteinase complexes was paralleled by a concomit...